A Genetic Atlas of Human Admixture History

A Genetic Atlas of Human Admixture History (Science, 2014)

G. Hellenthal, G.B.J. Busby, G. Band, J.F. Wilson, C. Capelli, D. Falush & S. Myers

Admixture occurs when two or more genetically distinguishable groups of individuals come together and have offspring. We analysed 95 populations to assess the presence of admixture across different worldwide groups. To understand the extent to which admixture has affected modern human populations, we developed a statistical tool, called GLOBETROTTER, that identifies whether or not admixture has taken place, and if so, what the likely source groups of this admixture were, and when this admixture happens. The major result of the paper was that most human populations have undergone some level of admixture over the last 4,000 years. Often, when we identify the sources and timing of admixture, the genetic admixture events match with known historical events. Below is a summary figure of some of our findings; we also have an interactive online atlas describing the full results of the paper here [http://admixturemap.paintmychromosomes.com/]

Hellenthal2014GeneticAtlasOfHumanAdmixtureHistory

Below you can find the dataset used in Hellenthal et al. 2014: A Genetic Atlas of Human Admixture History. As detailed in the paper, this data has been merged from multiple different sources, undergone QC to remove SNPs with low missingness, and has been phased using SHAPETIv2. This dataset contains 474,491 SNPs typed on 1530 individuals (human genome b36 coordinates). Any questions? please contact George Busby george@well.ox.ac.uk

Data from this study can be found here.

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